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Drug Actions Side Effects Storage
Synarel (Nasal Spray)
or
Lucrin
(subcutaneous injection)
(Agonists)
or
Decapeptyl
(Subcutanes injection)
 •Act on the pituitary gland to prevent premature ovulation in IVF cycles. Also provide a more controlled situation for ovarian stimulation and the production of follicles
 • May also be used to induce ovulation before Egg Pick-Up (EPU)
 • mild headaches
• hot flushes
• mood swings
• breast tenderness
• vaginal dryness
• changed sex drive
Synarel:
store below 25ºC
Lucrin: refrigerate
Decapeptyl: refrigerate
Cetrotide
or
Orgalutran
(Antagonists)
 • Used in IVF to prevent premature ovulation by stopping the normal rise in Luteinising Hormone (LH) that triggers ovulation • headaches
• nausea
• itchiness
• soreness and redness over the injection site
 Cetrotide:
store below 25ºC
Orgalutran:
store below 30ºC
Puregon
or
Gonal F (FSH)
or
Elonvaor
or
Menopur
or
Bemfola
or
Rekovelle
(subcutaneous injection)
 • Fertility hormones prescribed to encourage the development of follicles in the ovary to help recruit multiple eggs • abdominal tenderness and swelling
• breast tenderness
• mood swings
• nausea
• dizziness
• headaches
• fluid retention
• tender ovaries
• Ovarian Hyperstimulation Syndrome (OHSS)
 Refrigerate
Luveris
 • Helps to stimulate follicles in patients with low Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH) levels. Used with FSH  • soreness and redness over the injection site
• headaches
• nausea
 Store at room temperature below 25ºC
Pergoveris
 • Combination of FSH and LH prescribed to encourage the development of folicles in the ovary to help recruit multiple eggs  • abdominal tenderness and swelling
• breast tenderness
• mood swings
• nausea
• dizziness
• headaches
• fluid retention
• tender ovaries
• Ovarian Hyperstimulation Syndrome (OHSS)
 Store at room temperature below 25ºC and protect from light
Pregnyl
or
Ovidrel
(subcutaneous injection)
 • Induces ovulation before EPU and supports the lining of the uterus after embryo transfer. It is usually given 34–36 hours before egg collection and is commonly known as a “trigger” injection  • nausea
• abdominal bloating
• constipation
• soreness and redness over the injection site
• breast tenderness
• tender ovaries
• Ovarian Hyperstimulation Syndrome (OHSS)
Refrigerate
Crinone Applicators
Oripro Pessaries
(Luteal medications)
Endometrin
(Inserted into the vagina)
Utrogestan
(Inserted into the vagina)
 • Contain a natural progesterone hormone that is prescribed to support the lining of the uterus after embryo transfer in IVF treatment  • uterine cramping
• headaches
• sleepiness
• dizziness
• nausea
• abdominal pain
• constipation
• difficulty passing urine
• thrush-like symptoms
 Crinone:
store below 30ºC
Progesterone:
refrigerate
Endometrin:
store below 25ºC
Utrogestan:
store below 30ºC
Clomid
or
Serophene
 • Increases hormone production to help produce eggs and regulates ovulation  • abdominal discomfort
• nausea
• breast tenderness
• headaches
• sleeplessness
• mood swings
 Store below 30ºC
Progynova
(oral tablet)
 • Progynova is a synthetic hormone replacement for estrogen. It is used to build up the lining of the uterus in preparation for embryo transfer during a frozen cycle for women who do not ovulate regularly  • breast tenderness
• bloating
• mood changes
• nausea
• headaches
 Store at room temperature below 25ºC

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